Analysis of De Novo Missense A-alpha Mutations Associated with Intellectual Disabilities in the PP2A Holoenzyme
Intellectual disability (ID) is a genetic disorder characterized by limitations in intellectual capabilities, such as below-average cognitive functioning and deficiencies in social and practical skills, which affects 1-2% of the world population (Hu et al., 2015). A recent study by Houge et al. presented information on cases of ID that identified de novo missense mutations … [Read more…]