The purpose of the present study was to examine differences in mean R wave amplitude across 5 experimental paradigms among women with bulimia nervosa (n=12), women with subclinical binge/purge symptoms (n=20), and asymptomatic women (n=20) in order to assess risk for ventricular cardiac dysfunction across groups. Specifically, mean R wave amplitude was assessed via 3-lead electrocardiography (ECG) during 5-minute intervals recorded during supine posture (baseline supine rest), immediately following a posture shift to a seated position (posture shift 1), 5-minutes after a posture shift (posture shift 2), immediately after a 3-minute static handgrip exercise protocol (postexercise 1), and 5-minutes after exercise (postexercise 2). Results indicated statistically significant differences in mean R wave amplitude as a function of eating disorder status. Women with bulimia nervosa and women with subclinical binge/purge symptoms demonstrated significantly reduced mean R wave amplitudes compared to asymptomatic women. This may represent an important cardiac biomarker for cardiac risk in eating disorder populations.
Kristen Fernandez-Kong, ’15
Ewa Beach, HI
Additional Authors: Tyler Thorne ‘15 (Waimea, HI) Mary Willis ‘15 (Osceola, WI) Shuhan Reyes ‘16 (Houston, TX Jessie Lingbert ‘15 (Forest Lake, MN) Ruby Linkhart ‘16 (Denver, CO) Molly Johnson ‘15 (Boulder, CO), Melinda Green, & Jen Rogers
Sponsor: Melinda Green