Yeast (S. cerevisiae) are a relatively simple, ubiquitous, single-cell organism, like bacteria. However, unlike bacteria, yeast are eukaryotes, like humans. They also have some proteins that are similar to those found in humans. Some of the proteins are TOR proteins, which are responsible for many things, including resource partitioning. For this reason, TOR proteins influence a variety of issues, such as obesity and cancer. I analyzed yeast which had a temperature sensitive defunct version of the Tor2 protein. By altering their environment, I was able to partially alleviate the negative effects of the faulty protein. Moving forward I am studying the pathways that allow my environmental manipulations to suppress the mutations, in the hope that I may determine more effective methods of alleviating the effects of the faulty protein.
Andrew Anderson, ’13
Wonder Lake, IL
Majors: Biochemistry and Molecular Biology, Biology
Sponsor: Jeffrey Cardon